OptiLink Carboxylate-modified particles
OptiLink carboxylate-modified particles contain carboxylic acid groups for covalent coupling and can be used in a variety of applications.The various acid content available within the Opti-Link product line enables you to control such important parameters as sensitivity, specificity and stability. For most applications, Opti-Link particles can be used directly from the bottle without any pre-cleaning. Our proprietary anionic surfactant does not interfere with the binding of proteins, nor cause proteins to desorb from particle surfaces. Various surface acid concentrations are available to help optimize reagent development efforts.
Parking area combines surface area and acid content to give you the surface acid distribution that is useful for assay optimization. The surface area per gram of a particle varies inversely with the particle diameter. Acid content refers to the titrated milliequivalents per gram (mEq/g) and is weight-based.
Parking area properties
Low Acid Content—60–100 Parking Area—Hydrophobic surface, more colloidally stable than plain polystyrene
Medium Acid Content—35–59 Parking Area—Hydrophobic and hydrophilic areas; good colloidal stability and good covalent coupling
High Acid Content—10–34 Parking Area—Hydrophilic surface; excellent colloidal stability; excellent covalent coupling
The included traceable amount of proprietary anionic surfactant does not interfere with binding of proteins nor cause proteins to desorb from particle surfaces.
Various surface acid concentrations available to help optimize reagent development efforts.
OptiLink particles have been used in and are equally successful in molecular biology and research applications.
Storage Conditions: Store at 2° to 8°C.
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Recommended for: Clinical diagnostics, molecular biology, nephelometric, turbidimetric and slide agglutination assays
When using OptiLink particles, ask about our Microparticle Reagent Optimization manual, which outlines our reagent development strategy. This manual includes validated binding, coupling and particle reagent optimization protocols. Package Includes Package Insert and Certificate of Analysis
Standard Packaging Available in 15mL, 100mL, 1000mL, 10% solids concentration, 100mg/mL
Suggested Storage: 2 to 8°C
Specialty Packaging: OptiLink Carboxylate-Modified Polystyrene particles are available in different concentrations and package sizes upon request.
Sample Evaluation Packs: Packaged in 15mL bottles at 10% solids. The evaluation pack consists of three lots from all available PS or CM particles.
see coupling procedure: