Sera-Mag® SpeedBeads™ Magnetic Protein A/G coated Particles
Sera-Mag® Magnetic SpeedBeads™ Protein A/G Particles with conjugated recombinant Protein A/G. Recombinant Protein A/G which contains the IgG binding domains of Protein A and Protein G:
- 4 IgG binding domains from Protein A
- 2 IgG binding domains from Protein G
This enables the capture of antibody from a wide range of species and subclasses.
SpeedBeads Protein A/G Particles can be used for isolating antibodies from serum, cell culture supernatant or ascites, and for immunoprecipitation and co-immunoprecipitation of antigens from cell or tissue extracts.
These nominal 1µm magnetic particles of uniform size feature two layers of magnetite, resulting in faster magnetic response times, while the surface is modified with a proprietary method that minimizes non-specific binding of proteins. Protein A/G is then covalenty bound to the particle surface. The presence of Protein A/G enables use with the broadest range of antibody species and subclasses, which is ideal for antibody purification immunoprecipitations, and co-immunoprecipitation applications.
Manual and automated magnetic isolation of IgA and IgG proteins is accomplished in a single isolation instead of running two separate isolations.
Results from accelerated stability study project shows that SpeedBeads Protein A/G Particles are stable at
2 - 8°C for at least 2 years.
Sera-Mag SpeedBeads Protein A/G
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